By Bikramjit Basu, Dhirendra S. Katti, Ashok Kumar
Chapter 1 basics of Biomaterials and Biocompatibility (pages 1–18): Bikramjit Basu and Shekhar Nath
Chapter 2 basics of Hydroxyapatite and similar Calcium Phosphates (pages 19–52): Racquel Zapanta LeGeros, Atsuo Ito, Kunio Ishikawa, Toshiro Sakae and John P. LeGeros
Chapter three fabrics for Orthopedic functions (pages 53–100): Shekhar Nath and Bikramjit Basu
Chapter four The Micro Macroporous Biphasic Calcium Phosphate proposal for Bone Reconstruction and Tissue Engineering (pages 101–141): man Daculsi, Franck Jegoux and Pierre Layrolle
Chapter five technology and know-how built-in Titanium Dental Implant structures (pages 143–177): Yoshiki Oshida and Elif Bahar Tuna
Chapter 6 Injectable Hydrogels as Biomaterials (pages 179–203): Lakshmi S. Nair, Cato T. Laurencin and Mayank Tandon
Chapter 7 Nanomaterials for more advantageous Orthopedic and Bone Tissue Engineering purposes (pages 205–241): Lijie Zhang, Sirinrath Sirivisoot, Ganesh Balasundaram and Thomas J. Webster
Chapter eight creation to Processing of Biomaterials (pages 243–276): Dhirendra S. Katti, Shaunak Pandya, Meghali Bora and Rakesh Mahida
Chapter nine Laser Processing of Orthopedic Biomaterials (pages 277–322): Rajarshi Banerjee and Soumya Nag
Chapter 10 Functionally Graded All Ceramic HIP Joint (pages 323–356): Omer Van der Biest, man Anne, Kim Vanmeensel and Jef Vleugels
Chapter eleven clinical units in keeping with Bioinspired Ceramics (pages 357–409): Pio Gonzalez, Julian Martinez?Fernandez, Antonio R. de Arellano?Lopez and Mrityunjay Singh
Chapter 12 Ionomer Glasses: layout and Characterization (pages 411–433): Artemis Stamboulis and Fei Wang
Chapter thirteen Designing Nanofibrous Scaffolds for Tissue Engineering (pages 435–497): Neha Arya, Poonam Sharma and Dhirendra S. Katti
Chapter 14 layout of Supermacroporous Biomaterials through Gelation at Subzero Temperatures—Cryogelation (pages 499–531): Fatima M. Plieva, Ashok Kumar, Igor Yu. Galaev and Bo Mattiasson
Chapter 15 Biomaterial functions (pages 533–550): Ashok Kumar, Akshay Srivastava and period Jain
Chapter sixteen Cell?Based Nanocomposites and Biomolecules for Bone Tissue Engineering (pages 551–588): Michelle Ngiam, Susan Liao, Casey Chan and S. Ramakrishna
Chapter 17 Orthopedic Interface Tissue Engineering: development the Bridge to built-in Musculoskeletal Tissue platforms (pages 589–611): Helen H. Lu, Kristen L. Moffat and Jeffrey P. Spalazzi
Chapter 18 Cells of the anxious process and electric Stimulation (pages 613–642): Carlos Atico Ariza and Surya ok. Mallapragada
Chapter 19 Placental Umbilical wire Blood: a real Blood alternative (pages 643–662): Niranjan Bhattacharya
Chapter 20 Supported mobilephone Mimetic Monolayers and their Blood Compatibility (pages 663–676): okay. Kaladhar and Chandra P. Sharma
Chapter 21 Titanium Nitride and Diamond Like Carbon Coatings for Cardiovascular purposes (pages 677–705): C. V. Muraleedharan and G. S. Bhuvaneshwar
Read or Download Advanced Biomaterials: Fundamentals, Processing, and Applications PDF
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Extra resources for Advanced Biomaterials: Fundamentals, Processing, and Applications
1. Concept triangle illustrating the synergistic interaction of Engineering and Biological science disciplines, involved in designing biomaterials. The schematic also demonstrates the multidisciplinary approach of the science and technology of biomaterials. ] be replaced by various biomaterials. In living humans, most orthopedic/prosthetic joints and dental restorations demand the use of hard tissue/cortical bone or analogue materials, such as high-strength metals or high-hardness ceramics. To this end, the use of softer polymeric materials is restricted to the cranial area, blood vessels, heart valves, intraocular lenses, and so on.
The test is generally done in a laboratory using some standard/ relevant cell lines and the cells are seeded on the materials. As far as the experimental evaluation of biocompatibility is concerned, the cytotoxicity tests are widely cited as the primary assessment of biocompatibility and therefore are discussed in more detail below. As a first step, the sterilization of the samples is carried out in order to remove other micro-organisms, if present on the surface. , chemistry and chemical composition), the sterilization is either carried out in steam autoclave (15 psi, 121 °C, 20 minutes) or using γ-ray irradiation.
This reduction takes place only when mitochondrial reductase enzymes are active, and therefore, conversion is directly related to the number of viable (living) cells. • • Genotoxicity: In this in vitro experiment, it is primarily observed whether any genetic mutation occurs in the cells in direct contact with the biomaterial surface. Hemocompatibility: Hemocompatibility evaluates the material’s compatibility with red blood cells. In particular, thrombogenic property or changes in RBC content in a blood stream flowing over the biomaterials are assessed and a better thrombus material should ideally show limited thrombus formation.