Download Bioactive Materials in Medicine: Design and applications by X. Zhao, J M Courtney, H Qian PDF

By X. Zhao, J M Courtney, H Qian

 Initial chapters specialise in the basics of bioactive fabrics with chapters on such themes as nanotechnology and tissue engineering. additional chapters talk about laboratory layout concepts in an effort to medical functions. the ultimate few chapters evaluation present biomedical functions reminiscent of drug supply, gene remedy, cosmetic surgery and the longer term course of this more and more vital box.

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Ideally, the concentration of the therapeutic protein should be maintained continuously within the © Woodhead Publishing Limited, 2011 Bioactive materials with controlled bioactivity 23 therapeutic range for a prolonged time period to ensure the optimal therapeutic effects, without toxicity and unfavourable side effects. A controlled delivery system has been designed to form a polymer matrix in situ from an injected aqueous polymer solution and the hydrogel produced is used as storage for sustained release of the incorporated therapeutic substance, thus avoiding an invasive surgical placement.

Chemical activation of the substrate surface) instead of plasma for coupling CS to the surface [81]. At the present stage, a novel approach to the fabrication of porous scaffolds with surface-immobilised nano-hydroxyapatite (N-Hap) has been developed for effective bone tissue engineering. The discrete nano-level anchoring of N-Hap exposed on the pore surface of CS scaffolds expressed high specific surface area, excellent protein/cell binding ability and © Woodhead Publishing Limited, 2011 40 Bioactive materials in medicine osteoconductivity, and showed much improved surface properties for cell adhesion and growth.

Biomaterials, 2003, 24, 2133–2151. Anselme K. Osteoblast adhesion on biomaterials. Biomaterials, 2000, 21, 667– 681. Mrksich M. What can surface chemistry do for cell biology? Curr. Opinion Chem. , 2002, 6, 794–797. , and Honda H. The effect of RGD peptide- © Woodhead Publishing Limited, 2011 44 [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] Bioactive materials in medicine conjugated magnetite cationic liposomes on cell growth and cell sheet harvesting. Biomaterials, 2005, 26, 6185–6193.

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