By Eric S. Grace
(Joseph Henry Press) Revised variation goals to aid readers comprehend and participate in biotechnology debates. issues contain how biotechnology happened, instruments within the genetic engineering workshop, biotechnology and the physique, biotechnology at the farm, biotechnology and the surroundings, moral matters, and extra. For clinicians. past variation: c1997. Softcover.
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The hazards and disadvantages inherent in radioactivity-based equipment besides a verified and dramatic raise in sensitivity have brought on a massive shift in the direction of luminescence measurements and visualization concepts. Their use has now unfold even to standard scientific environments, and their purposes have grown from scientific assays to DNA sequencing, antioxidant detection, and high-throughput screening.
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Extra info for Biotechnology Unzipped: Promises And Realities, 2nd edition (2006)
If you could take the strand of DNA from one chromosome and lay it in a straight line, it would measure about 5 cm (2 in) long. With 46 chromosomes in a human cell, this means that the DNA content of one cell, stretched out and laid end to end, would be over 2 m (6 ft) in length! How much DNA is there in a human body? Enough to reach from here to the sun and back about 500 times. Nature is clearly an expert at packing. chromosome nucleus gene ribosome DNA double helix mitochondria nucleotide cell membrane cell Copyright © National Academy of Sciences.
The procedure involves destroying the nucleus Copyright © National Academy of Sciences. All rights reserved. html 48 BIOTECHNOLOGY UNZIPPED of an egg cell, then replacing it with the nucleus taken from any cell — say, a skin cell — of another individual. In the rare cases where success is achieved, the egg with the transplanted nucleus goes on to develop into a complete new organism identical to the one that supplied the skin cell nucleus. Nuclear transplanting was first successfully used to clone frogs, but animal cloning suddenly became a global news item following the birth of the celebrated sheep named Dolly in July 1996.
Hybridoma cells obtained in this way multiply and produce a continuous supply of antibodies called monoclonal because they are all descended from a single or clonal line of cells. Although monoclonal antibodies were originally developed for medical use, they have since found numerous applications as precise seek-and-find tools. Designed to attach themselves to a single particle type only, monoclonal antibodies have the ability to locate and mark any given target — without error — in any quantity in a mixture as complex as you care to produce.