Download Brain Oncology Biology, diagnosis and therapy: An by C. C. Tijssen (auth.), M. Chatel, F. Darcel, J. Pecker PDF

By C. C. Tijssen (auth.), M. Chatel, F. Darcel, J. Pecker (eds.)

The foreign assembly on mind Oncology in Rennes was once organised in honor of Jean Pecker, to pay tribute to his contribution to the improvement of neurological sciences and to take inventory of the present nation of data on mind tumors, a site within which the position of neurosurgery has been and should stay primordial. in the course of the two-day convention, the most important topics of mind oncology reviews, either basic and scientific, have been tested: oncogenesis, tumoral markers and immunology, metabolic and analysis imaging, prognostic components and healing ideas. the big quantity and prime quality of participations led to a surely man made view of present advances in study, of which this publication offers the necessities. now we have tried either to maintain the richness of medical exchanges which happened and to put up a good many oral and poster communications. The booklet respects the association of convention periods, and hence displays the significance accorded to glial tumor experiences. this can appear disproportionate given their frequency of prevalence in percentage to overall numbers of intracranial tumor approaches, yet their gravity and quasi-total resistance to present healing tools are plentiful justification. in addition, this is often the area within which hopes of development are commencing to look, and it's changing into attainable to envisage therapy in keeping with lately proven basic knowledge.

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Additional resources for Brain Oncology Biology, diagnosis and therapy: An international meeting on brain oncology, Rennes, France, September 4–5, 1986, held under the auspices of the Ministry of National Education, the University of Rennes and the Regional Hospital Rennes

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The preliminary results are shown in Table 3. Glioma grade 3 DISCUSSION TABLE 2 Expression of HA-ras and Ki-ras in human brain tumors as compared to normal human and rat tissues (RNA-DNA Dot blot). Sample Glioma grade 2 Glioma grade 4 Ki-ras + + + + + + + + + + + +++ +++ +++ + + + + + + + + + + + +++ +++ +++ 3 46 49 5 20 38 Medulloblastoma Meningioma n" 12 n' 31 n' 33 Neurinoma Normal human brain n" 50 Normal rat brain n" 8 n' 9 n" 10 Involvement of HSV, SV40 and Ad2 viruses in human brain tumors This study suggests that the viruses HSV, SV40 and Ad2 are not implicated in human brain tumors.

J. Mol. , 98,503-517 (1975). 18. ): DNA related to the transforming gene(s) of avian sarcoma virus is present in normal avian DNA. Nature, 260, 170-173 (1976). 19. ): Localization of the coding region for a 35 000 Dalton polypeptide on the genome of Herpes Simplex virus type 2. J. Gen. , 64, 2079-2085 (1983). H. BIGNER (0). INTRODUCTION Karyotypic evaluation of lymphomas, leukemias and solid tumors has demonstrated that specific chromosomal abnormalities characterize many of these processes (1).

Journal of Clinical Pathology, 38, 165-173. 3. ) (1986): Contribution des methodes immunohistochimiques it l'etude des tumeurs du systeme nerveux central. Annales de Pathologie, 6, 157-163. 4. ) (1986): Immunohistochemical signposts - not markers - in neural tumour differentiation. Neuropathology and Applied Neurobiology in press. 5. ) (1985): Glial fibrillary acidic protein (GFAP): the major protein in glial intermediate filaments in differentiated astrocytes. Journal of Neuroimmunology 8, 203-214.

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